This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008]
Function
GDP-dissociation inhibitor activity; Ras GTPase binding; identical protein binding; protein binding
Synonyms
SH3BP4; SH3-domain binding protein 4; TTP; BOG25; SH3 domain-binding protein 4; EH-binding protein 10; transferrin receptor-trafficking protein
Citations
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