This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009]
Function
ligase activity; poly(A) RNA binding; protein binding; zinc ion binding
Synonyms
MEX3C; mex-3 RNA binding family member C; RKHD2; BM-013; MEX-3C; RNF194; RNA-binding E3 ubiquitin-protein ligase MEX3C; RING finger protein 194; RNA-binding protein MEX3C; ring finger and KH domain containing 2; RING finger and KH domain-containing protein 2
Citations
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