RuV Capsid, recombinant protein from E. coli
Recombinant Rubella virus capsid region. Does not contain a fusion partner, was expressed in E. coli. Immunoreactive with Rubella virus positive sera.
> 95% pure (10% PAGE, coomassie staining). Sepharose derived purification
25mM Tris-HCl containing 10mM glutathione, 0.2% sarcosyl, 50% glycerol
2-8°C short term, -20°C long term
Rubella virus is an enveloped positive-strand RNA virus of the family TOGAVIRIDAE: Virions are composed of three structural proteins: a capsid and two membrane-spanning glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids.
Rubella virus is an enveloped positive-strand RNA virus. The genome encodes two open reading frames (ORFs): the 5"-proximal ORF encodes viral nonstructural proteins (NSP) that are responsible for viral genome replication, while the 3"-proximal ORF encodes three virion structural proteins (SP), the capsid protein (CP), and the two envelope glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids. The rubella virus (RV) structural proteins: capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of the capsid protein after cleavage by signal peptidase.
Coat protein; german measles; german measles capsid protein; p110; rubella capsid; Structural polyprotein; Rubella Virus Capsid; Togaviridae; Rubivirus