Human Thrombopoietin (DAG344)

Human Thrombopoietin, recombinant protein from E. coli Datasheet

Online Inquiry Add to basket

Nature
Recombinant
Tag/Conjugate
Unconjugated
Format
Purified, Lyophilized Reconstitute in 5mM Tris, pH 8.0 to aconcentration of 0.5-1.0 mg/ml. This solution can be diluted into otheraqueou buffers and stored at 2-8°C (up to one week) or –20°C for future use.
Concentration
Notapplicable
Buffer
Lyophilizedfrom 5mM Tris, pH 8.0
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5 UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
Antigen Description
Thrombopoietin (leukemia virus oncogene ligand, megakaryocytegrowth and development factor), also known as TPO, is a glycoprotein hormoneproduced mainly by the liver and the kidney that regulates the production ofplatelets by the bone marrow. It stimulate
Keywords
THPO; thrombopoietin; ML; TPO; MGDF; MKCSF; MPLLG; THCYT1; MPL ligand; c-mpl ligand; prepro-thrombopoietin; megakaryocyte stimulating factor; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia

Citations


Have you cited DAG344 in a publication? Let us know and earn a reward for your research.

Related Products


Human THPO peptide (DAG-P1251)

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Human Thrombopoietin

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket