Human Sjogren Syndrome Type B [His] (DAG602)

Human Sjogren Syndrome Type B [His], recombinant protein from Baculovirus Datasheet

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Product Overview
RecombinantFull-length cDNA coding for the human La protein fused to a hexa-histidine purificationtag. Expressed by recombinant baculovirus (Autographa californica multiplenuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9insect ce
> 90%(SDS-PAGE)
0.6-1.1 μg/ml (depending on the type ofELISA plate and coating buffer). Suitable for biotinylation and iodination.
Ionicstrength between 120 and 150mM salt, neutral to slightly alkaline pH and 20%glycerol as cryoprotective agent.
2-8°C short term, -20°C long term
The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
Antigen Description
It appears incorrectly here because of technical restrictions.SS-B also known as Lupus La protein is aprotein that in humans is encoded by the SSB gene.
SSB; Sjogren syndrome antigen B (autoantigen La); lupus La protein; La; La ribonucleoprotein domain family; member 3; LARP3; MGC118101; Sjoegren syndrome type B antigen; Autoantigen La; La; La autoantigen; La autoantigen homolog; La protein; La ribonucleo


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