HPV type 16 [GST] (DAG1573)

HPV type 16 [GST], recombinant protein from E. coli

Product Overview
Recombinant HPV 16 Protein fused to a GST-Tag was expressed in E. coli and purified by GSH affinity chromatography technique.
Nature
Recombinant
Tag/Conjugate
GST
Procedure
0.5mM EDTA
Purity
Greater than 95% pure as determined by 10% PAGE (Coomassie staining).
Buffer
formulated with 1x PBS and 0.5mM EDTA.
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
The Papillomavirus article covers the general biological features of human and animal papillomaviruses. Human papillomavirus (HPV) is a virus from the papillomavirus family of viruses that is capable of infecting humans. Like all papillomaviruses, HPVs establish productive infections only in keratinocytes of the skin or mucous membranes. While the majority of the nearly 200 known types of HPV cause no symptoms in most people, some types can cause warts (verrucae), while others can – in a minority of cases – lead to cancers of the cervix, vulva, vagina, and anus in women or cancers of the anus and penis in men. It can also cause cancers of the head and neck (tongue, tonsils and throat). Recently, HPV has been linked with an increased risk of cardiovascular disease.
Antigen Description
L1 is a major capsid protein of type 18 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.
Keywords
HPV 16; HPV; Human papillomavirus (HPV); Papillomaviridae; Human Papilloma Virus Type 16; Human Papilloma Virus; Human papillomavirus type 16 L1; Human papillomavirus type 16 E6; Human papillomavirus type 18 E6; Human papillomavirus type 16 major capsid p

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