Recombinant HSV gG protein fused with 26 kDa GST-tag containing the HSV-2 gG immunodominant regions, 525-578 amino acids was expressed in E. coli and purified by proprietary chromatographic technique.
> 95% pure as determined by 10% PAGE (coomassie staining).
0.1% SDS, 100mM NaCl, 50% glycerol.
2-8°C short term, -20°C long term
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus. Herpes simplex can be spread through contact with saliva, such as sharing drinks.
HSV2 is a member of the herpes virus family, Herpesviridae. All herpes viruses are morphologically identical. They have a large double stranded DNA genome. The virion consists of an icosahedral nucleocapsid which is surrounded by a lipid bilayer envelope. Between the capsid and the envelope is an amorphous layer of proteins, termed the tegument. Glycoprotein G (gG) is one of seven envelope glycoproteins in HSV2.
Herpes simplex virus-2 gG; HSV-2 gG