Product Overview
Recombinant Herpes Simplex Virus-1 (HSV-1) antigen (40.6 kDa), contains HSV-1 gD immunodominant region and a GST fusion partner, was expressed in E. coli, and puried in vitro using Metal affinity chromatography techniques.
Purity
> 95% pure (10% PAGE Coomassie staining). GS-4B Sepharose Affinity Purification
Buffer
25mM Tris-HCl, 1mM EDTA containing 50% glycerol
Storage
2-8°C short term, -20°C long term
Introduction
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus.
Antigen Description
Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
Keywords
Herpesviridae; Alphaherpesvirinae; Simplexvirus; Herpes simplex virus 1; HSV-1; Herpes simplex virus 2; HSV-2; Herpes simplex virus; HSV 1&2; Herpes Simplex Virus Type 1 & 2; HSV1 + HSV2 gD; Envelope glycoprotein D; GD; Glycoprotein D; US6
Datasheet