HSV type 1 Glycoprotein D (DAG2010)

HSV type 1 Glycoprotein D (aa 266 - 394), recombinant protein from E. coli

Product Overview
The E.Coli derived recombinant protein contains the HSV-1 gD immunodominant regions, 266-394 amino acids.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Procedure
None
Purity
> 95%, based on SDS PAGE
Format
Each vial contains 100 μg of lyophilized protein in 25mM Tris-HCl, 1mM EDTA, and 50% glycerol.
Concentration
N/A
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Herpes simplex virus type 1 (HSV1) is usually associated with infections of the lips, mouth, and face. It is the most common herpes simplex virus and is usually acquired in childhood. HSV-1 often causes lesions inside the mouth such as cold sores (fever blisters) and is transmitted by contact with infected saliva.
Antigen Description
Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
Keywords
GD; Glycoprotein D; Herpes simplex virus type 1 glycoprotein D; HSV1 glycoprotein D; US6; HSV1 gD; HSV1 gD; Recombinant Herpes simplex virus 1 gD

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References


Hirano, M; Nakamura, S; et al. Efficacy of a B virus gD DNA vaccine for induction of humoral and cellular immune responses in Japanese macaques. VACCINE 20:2523-2532(2002).
EBERLE, R; BLACK, DH; et al. HERPESVIRUS PAPIO-2, AN SA8-LIKE ALPHA-HERPESVIRUS OF BABOONS. ARCHIVES OF VIROLOGY 140:529-545(1995).

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