HIV type 2 Glycoprotein 32 [Biotin] (DAG1557)
HIV type 2 Glycoprotein 32 [Biotin], recombinant protein from E. coli
Datasheet
Product Overview
HIV-2 gp32 Biotin Labeled recombinant- contains the full-length sequence of HIV-2 envelope immunodominant regions gp32.
Nature
Recombinant
Tag/Conjugate
Biotin
Purity
Greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
Format
Sterile filtered colorless clear solution.
Buffer
20mM PBS pH-7.8, NaCl 0.5M, DTT 1mM, 8M urea and 0.4M imidasole.
Storage
2-8°C short term, -20°C long term
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.
Antigen Description
HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. gp 32 is a form of truncated gp41; gp41 is formed from the envelope protein, gp160.
Keywords
HIV-1 gp32; HIV1 gp32; Envelope surface glycoprotein gp32; Glycoprotein 32; gp32; gp32 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; Retroviridae; Lentivirus; human immunodeficiency virus; Env antibody; Env polyprotein; Envelope glyco
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