HIV type 1 P24 Capsid Protein (Q23-CxC) [His] (DAG2379)

HIV type 1 P24 Capsid Protein (Q23-CxC) [His], recombinant protein from HEK 293 cells Datasheet

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Product Overview
C-terminal 6xHis tagged p24 Capsid Protein (HIV-1/Clade A)(Q23-CxC) protein
Nature
Recombinant
Tag/Conjugate
His
Purity
≥ 95%
Format
Each vial contains 100 μg of purified protein in PBS.
Concentration
1 mg/ml
Storage
2-8°C short term, -20°C long term
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.
Antigen Description
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
Keywords
CA; Capsid protein p24; Human immunodeficiency virus 1; Human immunodeficiency virus type 1 p24; HIV1 p24

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