HIV type 1 Glycoprotein 41 [His] (DAG1798)

HIV type 1 Glycoprotein 41 (aa 534 - 681) [His], recombinant protein from HEK 293 cells Datasheet

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Product Overview
gp41 (HIV-1/HXBc2) (K03455, 534 a.a. - 681 a.a.) partial recombinant protein with His tag expressed in 293 cells.
Nature
Recombinant
Tag/Conjugate
His
Format
Liquid
Concentration
1 μg/μL
Buffer
In PBS (25% glycerol)
Storage
2-8°C short term, -20°C long term
Introduction
HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a Group M (major) and two or more minor groups.
Antigen Description
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
Keywords
HIV-1 gp41; HIV1 gp41 (HRP); Env; Env polyprotein; Envelope glycoprotein gp160; Envelope Protein gp120; Glycoprotein 41; GP120; gp41; Human Immunodeficiency Virus 1; Human Immunodeficiency Virus Type 1 gp41; TM; Transmembrane protein; Retroviridae; Lentiv

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