HIV type 1 Glycoprotein 160 (DAG1538)

HIV type 1 Glycoprotein 160, recombinant protein from Baculovirus Datasheet

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Product Overview
HIV-1 gp160 LAV Recombinant- is Full length 160 kDa, tetrameric, and glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. Purified under conditions that maintain the oligomeric structure of the molecule.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Purity
Greater than 90.0% as determined by HPLC analysis and SDS-PAGE.
Format
Sterile filtered colorless clear solution.
Buffer
10mM Tris pH-8, 0.3M NaCl and 0.01% Tween-20.
Storage
2-8°C short term, -20°C long term
Introduction
Endoproteolytic processing of human immunodeficiency virus type 1 (HIV1) gp160 membrane glycoprotein precursor into gp120 and gp41 is necessary for formation of infectious HIV particles. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Antigen Description
Endoproteolytic processing of human immunodeficiency virus type 1 (HIV1) gp160 membrane glycoprotein precursor into gp120 and gp41 is necessary for formation of infectious HIV particles. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Keywords
Envelope surface glycoprotein gp169; Glycoprotein 169; gp169; gp169 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; HIV-1 Gp169; Recombinant HIV-1 Gp169; Recombinant Human Immunodeficiency Virus Type 1, Gp169; rHu Immunodeficiency Virus

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