HIV type 1 TAT (DAG1551)

HIV type 1 TAT, recombinant protein from E. coli Datasheet

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Product Overview
HIV-1 TAT Cys22 Recombinant- produced in E.coli is a single, non-glycosylated, polypeptide chain containing 86 amino acids mutated in the trans activation domain and having chain having a molecular mass of 14.4 kDa.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Purity
Greater than 90.0% as determined by SDS-PAGE.
Format
Sterile Filtered White lyophilized (freeze-dried) powder.
Buffer
Lyophilized with 0.1% glycerol.
Storage
2-8°C short term, -20°C long term
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.
Antigen Description
Tat is an HIV gene.Tat stands for "Trans-Activator of Transcription". Tat consists of between 86 and 101 amino acids depending on the subtype.Also, in molecular biology, Tat is a protein which is encoded for by the Tat gene in HIV-1. Tat, is a regulatory protein that drastically enhances the efficiency of viral transcription.
Keywords
p14; Tat; Tat protein; Transactivating regulatory protein; HIV tat

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