HIV P24 (aa 231) [His], recombinant protein from P. pastoris
Recombinant HIV-1 p24 (a.a. 231 from strain HxB2), contains a 6 histidine fusion partner, was expressed in Pichia pastoris, reacts with HIV-1 positive human sera and monoclonal antibodies specific for conformational.
Purity verified by SDS-PAGE. Purity compares with reference lot.
0.02M Sodium phosphate, pH 6.5 to 7.5
2-8°C short term, -20°C long term
p24 is a component of the HIV particle capsid. There are approximately 2000 molecules per virus particle, or at a molecule weight of 24 kDa, about 10^4 virus particles per picogram of p24.
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
HIV1 p24; CA; p24; Human immunodeficiency virus type 1 p24; Capsid protein p24; HIV-1 p24; HIV 1 p24;