HIV type 1 Nef [Biotin] (DAG2934)

HIV type 1 Nef [Biotin], recombinant protein from E. coli Datasheet

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Product Overview
Recombinant (HIV-1) Nef biotin-conjugated. HIV-1 Nef is a 27kDa protein abundantly produced shortly after virus infection. Nef is an essential factor for efficient viral replication and pathogenesis, it also facilitates virus replication and enhances viri
Nature
Recombinant
Tag/Conjugate
Biotin
Purity
> 90% pure estimated by SDS-PAGE (EU Ph. 5.0 § 2.5.31)
Format
Liquid
Buffer
1X PBS, 0.05%(v/v) glycerol
Storage
2-8°C short term, -20°C long term
Introduction
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
Antigen Description
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
Keywords
Purified recombinant HIV1 Nef protein; HIV1 Nef protein; HIV-1 Nef protein; 3'ORF protein; ABIN protein; ABIN1 protein,C terminal core protein; F protein; Nef protein; Negative factor protein; p27 protein; VAN protein; Recombinant Human

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