HIV type 1 Nef [His] (DAG2315)

HIV type 1 Nef [His], recombinant protein from E. coli Datasheet

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Product Overview
C-terminal 6xHis tagged HIV-1 Nef (Clade C) protein
Nature
Recombinant
Tag/Conjugate
His
Purity
≥ 90%
Format
Each vial contains 100 μg of lyophilized protein in 500mM NaCl, 50mM Phosphat buffer (pH 7.4), 200mM Imidazole, 8M urea.
Concentration
1 mg/ml
Storage
2-8°C short term, -20°C long term
Introduction
HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). A total of 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence, but only few of them are functional.
Antigen Description
Nef (Negative Regulatory Factor) is a protein expressed by primate lentiviruses. These include human immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV). Nef is one of many pathogen-expressed proteins, known as virulence factors, which function to manipulate the host's cellular machinery and thus allow infection, survival or replication of the pathogen. Nef stands for "Negative Factor".
Keywords
HIV-1 Nef; Human immunodeficiency virus type 1 Nef

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Related Antibodies


HIV type 1 Nef (DAG-P2667)

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