Recombinant Hepatitis C Virus core Antigen
Core antigen; truncated from C-terminus
0.05M TRIS-saline, pH 8.0, 6M urea
2-8°C short term, -20°C long term
Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10, 000 nucleotides and encodes a single polyprotein of about 3, 000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein;
HCcAg; Core protein p19; HCV core antigen; HCV core protein; Hepatitis C Virus core protein; HCV-1 Core Ag; Hepatitis C Virus Core Antige, genotype 6a; Flaviviridae; Hepacivirus