HCV Core Antigen (DAG3071)

HCV Core Antigen, recombinant protein from P. pastoris

Product Overview
Recombinant Hepatitis C Virus core Antigen
Specificity
Core antigen; truncated from C-terminus
Nature
Recombinant
Tag/Conjugate
Unconjugated
Procedure
None
Purity
95% by SDS-PAGE
Buffer
0.05M TRIS-saline, pH 8.0, 6M urea
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10, 000 nucleotides and encodes a single polyprotein of about 3, 000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
Antigen Description
The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein;
Keywords
HCcAg; Core protein p19; HCV core antigen; HCV core protein; Hepatitis C Virus core protein; HCV-1 Core Ag; Hepatitis C Virus Core Antige, genotype 6a; Flaviviridae; Hepacivirus

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