Recombinant HCV type 5 Core Antigen (a.a. 2-119)

Product Overview

The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119.

Nature

Recombinant

Tag/Conjugate

Unconjugated

Purity

> 95%, based on SDS PAGE

Format

Each vial contains 100 μg of lyophilized protein in 50mM Tris-HCl, pH 8.0, 60mM NaCl, 10mM glutathione, 0.25% sarkosil 50% glycerol.

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10, 000 nucleotides and encodes a single polyprotein of about 3, 000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.

Keywords

HCcAg; Core protein p19; HCV core antigen; HCV core protein; Hepatitis C Virus core protein; HCV-1 Core Ag; Hepatitis C Virus Core Antige, genotype 6a; Flaviviridae; Hepacivirus