HBV type 3 PreS1 [BSA] (DAG2404)

HBV type 3 PreS1 (aa 1 - 445) [BSA], recombinant protein from E. coli Datasheet

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Product Overview
C-terminal 6xHis tagged PreS1-HBsAg (HBV/Genotype C) protein (a.a. 1-445)
Nature
Recombinant
Tag/Conjugate
BSA
Purity
> 95%, based on SDS PAGE
Format
Each vial contains 100 μg of lyophilized protein in PBS.
Concentration
N/A
Storage
2-8°C short term, -20°C long term
Introduction
Japanese encephalitis—previously known as Japanese B encephalitis to distinguish it from von Economo's A encephalitis—is a disease caused by the mosquito-borne Japanese encephalitis virus. The Japanese encephalitis virus is a virus from the family Flaviviridae. Domestic pigs and wild birds (herons) are reservoirs of the virus; transmission to humans may cause severe symptoms. Amongst the most important vectors of this disease are the mosquitoes Culex tritaeniorhynchus and Culex vishnui. This disease is most prevalent in Southeast Asia and the Far East.
Antigen Description
HBsAg is the surface antigen of the hepatitis B virus (HBV). It indicates current hepatitis B infection.The viral envelope of enveloped virus has different surface proteins from the rest of the virus which act as antigens. These antigens are recognized by antibody proteins that bind specifically to one of these surface proteins.The HBsAg gene is one long open reading frame but contains three in frame "start" (ATG) codons that divide the gene into three sections, pre-S1, pre-S2, and S. Because of the multiple start codons, polypeptides of three different sizes called large, middle, and small (pre-S1 + pre-S2 + S, pre-S2 + S, or S) are produced. The function of the protein coded for by gene X is not fully understood.
Keywords
Japanese encephalitis; Japanese encephalitis virus; JE; JEV; Flaviviridae; Flavivirus; PreM/M Protein

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