E. coli SecB (aa 1 - 155), recombinant protein from E. coli
Escherichia coli secB (NP_418066, 1 a.a. - 155 a.a.) full-length recombinant protein expressed inEscherichia coli .
In 20 mM Tris-HCl pH 8.0 (10% glycerol)
2-8°C short term, -20°C long term
Escherichia coli (/?????r?ki? ?ko?la?/; commonly abbreviated E. coli) is a gram-negative, facultatively anaerobic, rod-shaped bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in their hosts, and are occasionally responsible for product recalls due to food contamination. The harmless strains are part of the normal flora of the gut, and can benefit their hosts by producing vitamin K2, and preventing colonization of the intestine with pathogenic bacteria.
SecB is a protein chaperone which binds diverse ligands rapidly with high affinity and low specificity. It plays a crucial role during protein export via the general secretory pathway by modulating the partitioning of precursors between folding or aggregation and delivery to the membrane-bound translocation apparatus. SecB has the potential to participate in functions outside of export acting as a general nonspecific chaperone to provide buffering capacity of the nonnative state of proteins in the cytosolic pool.
b3609; JW3584; Protein export protein secB; secB; E. coli secB; Escherichia coli secB