E. coli MutM [His] (DAG2567)

E. coli MutM (aa 1 - 269) [His], recombinant protein from E. coli Datasheet

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Product Overview
mutM, 1-269 aa E.coli, His-tagged, Recombinant, E.coli
Nature
Recombinant
Tag/Conjugate
His
Purity
> 90% by SDS-PAGE
Format
Liquid. 20mM Tris-HC buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT
Concentration
0.5 mg/ml (determined by Bradford assay)
Storage
2-8°C short term, -20°C long term
Introduction
Escherichia coli (/?????r?ki? ?ko?la?/; commonly abbreviated E. coli) is a gram-negative, facultatively anaerobic, rod-shaped bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in their hosts, and are occasionally responsible for product recalls due to food contamination. The harmless strains are part of the normal flora of the gut, and can benefit their hosts by producing vitamin K2, and preventing colonization of the intestine with pathogenic bacteria.
Antigen Description
mutM, also known as formamidopyrimidine DNA glycosylase, is a base excision repair enzyme which recognizes and removes a wide range of oxidized purines from correspondingly damaged DNA. This protein is nonredundant and required to rapidly remove its substrate lesions on the chromosome. In addition, it also repaired a significant portion of the lesions recognized by Endo III, suggesting that it plays a prominent role in the global repair of both purine damage and pyrimidine damage in vivo.
Keywords
ECK3625; Formamidopyrimidine DNA glycosylase; Formamidopyrimidine/5 formyluracil/ 5 hydroxymethyluracil DNA glycosylase; Fpg; JW3610; E. coli mutM; Escherichia coli mutM

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