E. coli Fur (aa 1 - 148), recombinant protein from E. coli
Escherichia coli fur (NP_415209, 1 a.a. - 148 a.a.) full-length recombinant protein expressed inEscherichia coli .
In 20 mM Tris, 2 mM CaCl2, 100mM NaCl, pH 8.0
2-8°C short term, -20°C long term
Escherichia coli (/?????r?ki? ?ko?la?/; commonly abbreviated E. coli) is a gram-negative, facultatively anaerobic, rod-shaped bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in their hosts, and are occasionally responsible for product recalls due to food contamination. The harmless strains are part of the normal flora of the gut, and can benefit their hosts by producing vitamin K2, and preventing colonization of the intestine with pathogenic bacteria.
fur (ferric uptake regulator) protein is a DNA-binding protein which regulates iron-responsive genes. A small, 17-kDa, global transcriptional repressor, fur, in the presence of iron regulates functions as diverse as iron acquisition, oxidative stress, and virulence. In Escherichia coli, members of the fur family regulate the expression of more than 100 genes that function in processes as varied as the biosynthesis and transport of siderophores, the expression of virulence factors, the alleviation of oxidative and NO-induced stress, and the inhibition of ferritin production through the expression of RyhB.
DNA binding transcriptional dual regulator of siderophore biosynthesis and transport; ECK0671; Ferric uptake regulation protein; Ferric uptake regulator; FUR; JW0669; E. coli fur; Escherichia coli fur