E. coli NTH1 Protein [His], recombinant protein from E. coli
Recombinant E.coli nth protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Please see the vial label for concentration
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
2-8°C short term, -20°C long term
Escherichia coli is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans, and are occasionally responsible for product recalls due to food contamination. The harmless strains are part of the normal flora of the gut, and can benefit their hosts by producing vitamin K2, and by preventing the establishment of pathogenic bacteria within the intestine
Nth, also known as Endonuclease III, has an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. This enzyme incises damaged DNA at cytosines, thymines and guanines. Nth acts on a damaged strand, 5' from the damaged site. This enzyme is required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.
Escherichia coli; E. coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Gammaproteobacteria; EC 22.214.171.124 protein; endonuclease III-like protein 1 protein; nth endonuclease III-like 1 (E. coli) protein; OCTS3NTH1nth (E.coli endonuclease III)-like 1