Recombinant D. farina Der P1 Protein [His]

Product Overview

The E.Coli derived recombinant protein contains the Dermatophagoides pteronyssinus Dust Mite Der P1 protein (a.a. 20-320) and fused to a 6 His Tag at C-terminus, having a total Mw of 34.5kDa, pI 5.6.

Target

D. farina Der P1

Nature

Recombinant

Tag/Conjugate

His

Molecular Weight

34.5 kDa

Alternative Names

D. farina Der F1; DERF1; Der F2; D. farina

Purity

Protein is>95% pure as determined by 10% SDS-PAGE (coomassie staining).

Format

Liquid

Buffer

60mM NaCl and 50mM Tris-HCl pH 8.0.

Preservative

None

Storage

Der-P1 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.

Ship

Shipped with Ice Packs

Introduction

DERP1 is a thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues. DERP1 is a C1 peptidase family member. DERP1 has extensive endopeptidase specificity. DERP1 is N-glycosylated. N-glycanase treatment does not completely remove carbohydrates, suggesting that the protein contains additional glycosylation sites. DERP1 causes an allergic reaction in humans. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. DERP1 binds to IgE in 80% of patients with house dust allergy.

Keywords

D. farina Der P1; DERP1; Der P1; D. farina