Recombinant B. burgdorferi OspC protein [His] (DAGA-2006)

Borrelia burgdorferi Outer Surface Protein C (OspC) [His], recombinant protein from E.coli Datasheet

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Product Overview
B. burgdorferi Osp-C Recomb.
Borrelia burgdorferi Outer Surface Protein C (Osp-C) Recombinant
Contains a His-tag in its N-Terminus.
Molecular weight calculated from the amino acid sequence is 27.9 kDa.
Molecular Weight
27.9 kDa
Alternative Names
B. burgdorferi OspC; B burgdorferi; BB_B19; outer surface protein C Lyme disease; OspC; Osp-c
≥ 95% pure (SDS-PAGE).
Purified, Liquid
Batch dependent - please inquire should you have specific requirements
20 mM Phosphate Buffer, pH 7.0, 0.15 M Sodium Chloride.
Store at -20°C to -80°C. Aliquot and freeze to avoid multiple/freeze thaw cycles.
Antigen Description
Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response. OspC is a major surface protein produced by B. burgdorferi when infected ticks feed but whose synthesis decreases after transmission to a mammalian host.During mammalian infection, ospC transcript is reduced and OspC protein disappears from the bacterial surface around 2 weeks after infection.Because of this synthesis pattern, OspC was speculated to be required for some aspect of transmission, either migration of the spirochetes from the tick midgut to salivary glands and into the mammal or establishing an infection in the mammal.
B. burgdorferi OspC;B burgdorferi;BB_B19;outer surface protein C Lyme disease;OspC;Osp-c;Spirochaetaceae;Borrelia


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