Product Overview
Recombinant Borrelia burgdorferi Osp-C, contains multiple copies of the Osp-C sequence, contains a 6-His epitope tag. Total molecular weight is 85 kDa. It was expressed in E. coli. Reacts with human Borrelia burgdorferi positive serum.
Purity
> 95% as determined by SDS-PAGE
Concentration
1 mg/ml (Bradford method)
Buffer
20 mM Tris-HCl, pH 7.5 containing 10 mM Beta-Mercaptoethanol
Storage
Store at -20°C to -80°C
Introduction
Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response. B. burgdorferi resembles other spirochetes in that it is a highly specialized, motile, two-membrane, spiral shaped bacteria which lives primarily as an extracellular pathogen. B. burgdorferi has an unusual genome compared with other eubacteria which includes a linear chromosome approximately one megabase in size and numerous linear and circular plasmids.
Keywords
B burgdorferi; Lyme disease; Osp-c; Spirochaetaceae; Borrelia
Citations
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