Rat alpha 1-acid glycoprotein reference serum (DAGA-684)

Rat alpha 1-acid glycoprotein reference serum, native protein

Specificity
Rat
Nature
Native
Tag/Conjugate
Unconjugated
Alternative Names
Rat; Alpha 1-Acid Glycoprotein; Serum
Procedure
None
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements
Size
1ml
Preservative
0.1% Sodium Azide
Storage
Frozen -20°C
Antigen Description
Alpha-1-acid glycoprotein (α1AGp, AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein). Plasma levels are affected by pregnancy, burns, certain drugs, and certain diseases, particularly HIV.
Keywords
Rat;Alpha 1-Acid Glycoprotein;Serum

Citations


Have you cited DAGA-684 in a publication? Let us know and earn a reward for your research.

Related Products


Dog Serum (DAG124)
Pig Serum (DAG126)
Rabbit Serum (DAG138)

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Polycyclic aromatic hydrocarbon exposure results in altered CRH, reproductive, and thyroid hormone concentrations during human pregnancy

SCIENCE OF THE TOTAL ENVIRONMENT

Authors: Cathey, Amber L.; Watkins, Deborah J.; Rosario, Zaira Y.; Vega, Carmen M. Velez; Loch-Caruso, Rita; Alshawabkeh, Akram N.; Cordero, Jose F.; Meeker, John D.

Polycyclic aromatic hydrocarbons (PAHs) are byproducts of incomplete combustion reactions and are ubiquitous in the environment, leading to widespread human exposure via inhalation and ingestion pathways. PAHs have been implicated as endocrine disrupting compounds in previous animal and in vitro studies, but human studies are currently lacking. Pregnant women and their developing fetuses are particularly susceptible populations to environmental contaminants, in part because alterations in hormone physiology during gestation can have adverse consequences on the health of the pregnancy. We utilized data on 659 pregnant women from the PROTECT longitudinal birth cohort in Puerto Rico to assess associations between repeated measures of 3 urinary hydroxylated PAH (OH-PAH) metabolites and 9 serum hormones during gestation. Urine samples were collected at 3 study visits (median gestational ages of 18, 22, and 26 weeks at each visit, respectively) and serum samples were collected at the first and third study visits. Linear mixed effects models were used to ascertain longitudinal associations between OH-PAHs and hormones, and sensitivity analyses were employed to assess potential nonlinearity and differences in associations on the basis of fetal sex and timing of biomarker measurement. Among the multiple positive associations we observed between OH-PAHs and CRH, estriol, progesterone, T3, and the ratio of T3 to T4, and inverse associations with testosterone, the most notable are a 24.3% increase (95% Cl: 13.0, 36.7) in CRH with an interquartile range (1QR) increase in 1-hydroxyphenanthrene and a 17.2% decrease (95% CI: 8.13, 25.4) in testosterone with an 1QR increase in 1-hydroxynapthalene. Many associations observed were dependent on fetal sex, and some relationships showed evidence of nonlinearity. These findings demonstrate the importance of studying PAH exposures during pregnancy and highlight the potential complexity of their impacts on the physiology of human pregnancy. (C) 2020 Elsevier B.V. All rights reserved.

Hematologic and serum biochemical reference values in chemically immobilized free-ranging sambar (Rusa unicolor)

EUROPEAN JOURNAL OF WILDLIFE RESEARCH

Authors: Nigam, Parag; Talukdar, Animesh; Habib, Bilal; Pandav, Bivash; Malik, Pradeep K.; Kalyanasundaram, Sankar

Hematological and serum biochemical reference values for 33 free-ranging sambar deer following immobilization with medetomidine (70-100 mu gkg(-1)) and ketamine (1-2 mgkg(-1)) in Sariska Tiger Reserve in India were established and the differences across sex and age group were compared. Hematological and biochemical variables across different age-classes for red blood cell count, eosinophils, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, triglycerides, and blood glucose varied significantly though the hematological values did not vary between sexes. Blood urea nitrogen and creatinine levels were significantly influenced by sex in the present study. Interpretation of the result, however, needs to be made with caution due to the low number of sub-adult compared to adults in the present study. The study highlights the need for understanding the source of individual variation for meaningful interpretation. This paper provides the first report of baseline hematologic and serum biochemistry values for free-ranging sambar deer that can form basis for assessing the state of health and nutritional condition of the animal.

Online Inquiry

Name:
Phone: *
E-mail Address: *
Technology Interest:
Type of Organization:
Service & Products Interested: *
Project Description:
Verification code
Click image to refresh the verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket