Product Overview
Blocking/Immunizing peptide for anti-Ramp1 (C-Term., mouse) antibody
Target
Ramp1 (C-Term., mouse)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq, Jul 2008]
Function
calcitonin receptor activity; calcitonin receptor binding; coreceptor activity; coreceptor activity; protein transporter activity; receptor activity;
Synonyms
RAMP1; receptor (calcitonin) activity modifying protein 1; receptor activity-modifying protein 1; 9130218E19Rik; MGC38240;
Citations
Publication ()
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