This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Function
GDP binding; GTP binding; GTPase activity; protein binding; protein transporter activity;
Synonyms
RAB4A; RAB4A, member RAS oncogene family; RAB4; HRES1; HRES-1; HRES-1/RAB4; ras-related protein Rab-4A; HTLV-1 related endogenous sequence;
Citations
Publication ()
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