Human RNF8 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-RNF8 antibody

Target

RNF8

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Function

acid-amino acid ligase activity; chromatin binding; histone binding; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

Synonyms

RNF8; ring finger protein 8, E3 ubiquitin protein ligase; ring finger protein (C3HC4 type) 8 , ring finger protein 8; E3 ubiquitin-protein ligase RNF8; KIAA0646; C3HC4-type zinc finger protein; ring finger protein (C3HC4 type) 8; UBC13/UEV-interacting ring finger protein; FLJ12013;