Human RNF8 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

RNF8 peptide corresponds to 15 amino acids of RNF8.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Reconstitution

RNF8 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Entrez Gene ID

Synonyms

RNF8; ring finger protein 8, E3 ubiquitin protein ligase; hRNF8; E3 ubiquitin-protein ligase RNF8; C3HC4-type zinc finger protein; ring finger protein (C3HC4 type) 8; UBC13/UEV-interacting ring finger protein;