Human PCGF6 peptide

Specificity

Ubiquitous.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Contains 1 RING-type zinc finger.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Function

DNA binding; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;

Synonyms

PCGF6; polycomb group ring finger 6; MBLR; RNF134; polycomb group RING finger protein 6; ring finger protein 134; Mel18 and Bmi1-like RING finger protein;