This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]
Function
RNA binding; nucleotide binding; ribosomal large subunit binding;
Synonyms
RBM3; RNA binding motif (RNP1, RRM) protein 3; RNA binding motif protein 3; putative RNA-binding protein 3; IS1 RNPL; RNA-binding motif protein 3; RNPL; IS1-RNPL;
Citations
Publication ()
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References
RNA Binding Protein RBM3 Enhances Stem Cell Characteristics and Wnt/beta-Catenin Signaling in Colorectal Cancer
RNA Binding Motif Protein 3 (RBM3) Over-Expression Is Associated with Favorable Histopathological Findings but Not with Outcome in Urothelial Carcinoma of the Bladder