Product Overview
Quinolinic Acid, BSA-conjugated
Specificity
Quinaldinic Acid conjugated with bovine serum albumin (BSA).
Purity
Purity is greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
Storage
2-8°C short term, -20°C long term
Reconstitution
Reconstituted in deionized water (250 μg)
Introduction
Quinolinic acid is a naturally occurring toxin in the central nervous system believed to play a role in AIDS dementia complex. A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated csf levels of quinolinic acid are significantly correlated with the severity of neuropsychological deficits in patients who have aids.
Keywords
Pyridine 23 dicarboxylic Acid; Pyridine-2,3-dicarboxylate; 2,3-PyridinedicarboxylicAcid99%; Pyridin-2,3-dicarbonsaeure; 2,3-Pyridinedicarboxylic; 2,3-pyridine dicarbo
Citations
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GIULIAN, D; WENDT, E; et al. THE ENVELOPE GLYCOPROTEIN OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 STIMULATES RELEASE OF NEUROTOXINS FROM MONOCYTES. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90:2769-2773(1993).
Lehrmann, E; Molinari, A; et al. Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum. EXPERIMENTAL BRAIN RESEARCH 141:389-397(2001).
COA
Certificate of Analysis
