PSMB7 blocking peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

PSMB7 peptide is a synthetic peptide corresponding to the internal region of PSMB7.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Reconstitution

PSMB7 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]

Entrez Gene ID

Synonyms

PSMB7; proteasome (prosome, macropain) subunit, beta type, 7; Z; proteasome subunit beta type-7; macropain chain Z; proteasome subunit Z; proteasome subunit alpha; proteasome catalytic subunit 2; multicatalytic endopeptidase complex chain Z;