Specificity
Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the DNA polymerase type-B-like family.Contains 1 PAP-associated domain.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3 poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]
Function
ATP binding; UTP binding; identical protein binding; magnesium ion binding; manganese ion binding; poly(A) RNA binding; polynucleotide adenylyltransferase activity; protein binding; protein homodimerization activity;
Synonyms
MTPAP; mitochondrial poly(A) polymerase; PAPD1; SPAX4; poly(A) RNA polymerase, mitochondrial; TUTase 1; terminal uridylyltransferase 1; polynucleotide adenylyltransferase; PAP-associated domain-containing protein 1;
Citations
Publication ()
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