Human SPI1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-PU.1 antibody

Target

PU.1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

6688

UniProt ID

P17947

Antigen Description

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function

NFAT protein binding; RNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II distal enhancer sequence-specific DNA bind

Synonyms

SPI1; spleen focus forming virus (SFFV) proviral integration oncogene; OF; PU.1; SFPI1; SPI-1; SPI-A; transcription factor PU.1; SPI-1 proto-oncogene; 31 kDa transforming protein; 31 kDa-transforming protein; hematopoietic transcription factor PU.1; spleen focus forming virus (SFFV) proviral integration oncogene spi1;