Product Overview
Blocking/Immunizing peptide for anti-PREX1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]
Function
Rho GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; enzyme binding; guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding;
Synonyms
PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; KIAA1415; P REX1; ptdIns(3,4,5)-dependent Rac exchanger 1; P-REX1;
Citations
Publication ()
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COA
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