Product Overview
Blocking/Immunizing peptide for anti-PNKP/PNK antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010]
Function
ATP binding; ATP-dependent polydeoxyribonucleotide 5-hydroxyl-kinase activity; damaged DNA binding; double-stranded DNA binding; endonuclease activity; nucleotide kinase activity; polynucleotide 3-phosphatase activity; protein binding; purine nucleotide b
Synonyms
PNKP; polynucleotide kinase 3-phosphatase; PNK; MCSZ; EIEE10; bifunctional polynucleotide phosphatase/kinase; DNA 5-kinase/3-phosphatase; Homo sapiens polynucleotide kinase 3-phosphatase (PNKP);
Citations
Publication ()
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COA
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