Human PM/Scl100 [His], recombinant protein from Baculovirus
Recombinant human PM/Scl100, his-tagged
SDS-PAGE (purity > 70%); Western blot with i: polymyositis patient sera; ii: monoclonal anti-hexa-His-tag antibody.
0.4-0.8 μg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.
2-8°C short term, -20°C long term
PM/Scl 100 is a nucleolar protein and represents one crucial component of the so-called "PM/Scl complex" or "nuclear exosome", which is an RNA-processing complex consisting of a number of exoribonucleases (not to be confused with certain multivesicular bodies which are shed by cultured cells into the culture fluid and are also called exosomes)
exosome component 10; 9138; Ensembl:ENSG00000171824; exosome component 10; autoantigen PM-SCL; autoantigen PM/Scl 2; polymyositis/scleroderma autoantigen 100 kDa; polymyositis/scleroderma autoantigen 2 (100kD); polymyositis/scleroderma autoantigen 2, 100k