Human PM/Scl100 [His] (DAG4858)

Human PM/Scl100 [His], recombinant protein from Baculovirus Datasheet

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Product Overview
Recombinant human PM/Scl100, his-tagged
Nature
Recombinant
Tag/Conjugate
His
Purity
SDS-PAGE (purity > 70%); Western blot with i: polymyositis patient sera; ii: monoclonal anti-hexa-His-tag antibody.
Concentration
0.4-0.8 μg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.
Storage
2-8°C short term, -20°C long term
Antigen Description
PM/Scl 100 is a nucleolar protein and represents one crucial component of the so-called "PM/Scl complex" or "nuclear exosome", which is an RNA-processing complex consisting of a number of exoribonucleases (not to be confused with certain multivesicular bodies which are shed by cultured cells into the culture fluid and are also called exosomes)
Keywords
exosome component 10; 9138; Ensembl:ENSG00000171824; exosome component 10; autoantigen PM-SCL; autoantigen PM/Scl 2; polymyositis/scleroderma autoantigen 100 kDa; polymyositis/scleroderma autoantigen 2 (100kD); polymyositis/scleroderma autoantigen 2, 100k

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