Specifications
Immunogen
PI4KII (NP_060895, 383 aa ~ 477 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
phosphatidylinositol 4-kinase type 2 alpha; DKFZp761G1923; PI4KII; OTTHUMP00000221793; PIK42A; RP11-548K23.6; Phosphatidylinositol 4-kinase type II-alpha; phosphatidylinositol 4-kinase type 2-alpha; EC 2.7.1.67; phosphatidylinositol 4-kinase type II (PI4KII); OTTHUMP00000020224
Product Background
Antigen Description
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001Mouse monoclonal antibody raised against a partial recombinant PI4KII.
Pathway
3-phosphoinositide biosynthesis, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; D-myo-inositol (1, 4, 5)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem
Citations
Publication ()
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COA
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