Synthetic Human PAX6 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-PAX6 (internal) antibody
Human, Mouse, Rat
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
DNA binding; R-SMAD binding; RNA polymerase II core promoter sequence-specific DNA binding; histone acetyltransferase binding; protein binding; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcri
PAX6; paired box 6; AN2, paired box gene 6 (aniridia, keratitis); paired box protein Pax-6; AN; aniridia; keratitis; D11S812E; WAGR; oculorhombin; aniridia type II protein; paired box homeotic gene-6; AN2; MGDA; MGC17209;