The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Sep 2013)
Function
lipid binding;
Synonyms
OSBP2; oxysterol binding protein 2; OSBPL1; oxysterol-binding protein 2; KIAA1664; ORP 4; ORP4; OSBP-related protein 4; oxysterol binding protein-like 1; oxysterol binding protein-related protein 4; oxysterol-binding protein-related protein 4; ORP-4; OSBPL4;
Citations
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