Product Overview
Blocking/Immunizing peptide for anti-OASIS/CREB3L1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements.
Function
protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Synonyms
CREB3L1; cAMP responsive element binding protein 3-like 1; cyclic AMP-responsive element-binding protein 3-like protein 1; BBF 2 homolog (drosophila); OASIS; BBF-2 homolog; old astrocyte specifically induced substance; old astrocyte specifically-induced substance; cAMP-responsive element-binding protein 3-like protein 1;
Citations
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Thway, K; Fisher, C; et al. Claudin-1 is expressed in perineurioma-like low-grade fibromyxoid sarcoma. HUMAN PATHOLOGY 40:1586-1590(2009).
Debelenko, LV; McGregor, LM; et al. A Novel EWSR1-CREB3L1 Fusion Transcript in a Case of Small Cell Osteosarcoma. GENES CHROMOSOMES & CANCER 50:1054-1062(2011).