Tag/Conjugate
Unconjugated
Molecular Weight
~70 kDa for Reduced, ~80 kDa for Non-Reduced
Alternative Names
Beta-1 metal-binding globulin, Serotransferrin, Siderophilin, TF, Transferrin
Application Notes
Western Blot 1:100 - 1:2000
ELISA 1:100 - 1:2000
Purity
Immunoelectrophoresis (IEP)
Buffer
Lyophilized from 0.2 M ammonium bicarbonate.
Reconstitution
Reconstitute with 1.0 ml deionized water (or equivalent) to desired concentration.
Introduction
Human transferrin is encoded by the TF gene and is an iron-binding blood plasma glycoprotein that controls the level of free iron in biological fluids. Human transferrin binds iron very tightly but reversibly. Human transferrin is the most important iron pool in mammals. Human transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites. The affinity of Human transferrin for Fe(III) is extremely high but decreases progressively with decreasing pH below neutrality.
Keywords
Beta-1 metal-binding globulin; Serotransferrin; Siderophilin; TF; Transferrin
Citations
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