Specificity
The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Tag/Conjugate
Unconjugated
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
Function
magnesium ion binding; phosphopyruvate hydratase activity;
Synonyms
ENO2; enolase 2 (gamma, neuronal); NSE; HEL-S-279; gamma-enolase; neural enolase; neuron-specific enolase; neurone-specific enolase; neuron specific gamma enolase; 2-phospho-D-glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; epididymis secretory protein Li 279;
Citations
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Ramirez, GA; Rodriguez, F; et al. Morphologic and immunohistochemical features of Merkel cells in the dog. RESEARCH IN VETERINARY SCIENCE 97:475-480(2014).
Huseynova, S; Panakhova, N; et al. Elevated levels of serum sICAM-1 in asphyxiated low birth weight newborns. SCIENTIFIC REPORTS 4:-(2014).
COA
Certificate of Analysis
