Product Overview
Recombinant Hepatitis C Virus NS4 Mosaic Genotype-1(a.a. 1691-1710, 1712-1733, 1921-1940), GST-tagged
Specificity
Immunoreactive with sera of HCV-infected individuals.
Purity
Protein is > 95% pure as determined by 10% PAGE (coomassie staining).
Storage
2-8°C short term, -20°C long term
Introduction
HCV is a positive, single-stranded RNAvirus in the Flaviviridae family. The genome is approximately 10, 000nucleotides and encodes a single polyprotein of about 3, 000 amino acids.HCVis responsible for a large proportion of worldwide chronic viral hepatitides.Most of these infections develop into chronic hepatitis, which oftenprogresses to liver cirrhosis and hepatocellular carcinoma. At present, (unlike hepatitis A and B), there is no vaccine to prevent hepatitis Cinfection.The hepatitis C virus (HCV) nonstructural protein 4B (NS4B) is arelatively hydrophobic 27-kDa protein. The 4A protein has a molecular weight of 6 kDa.
Keywords
HCV; HCV NS4; Hepatitis C Virus nonstructural antigen 4; Non structural protein 4A; Non structural protein 4B; NS4A; NS4B; Flaviviridae; Hepacivirus; Hepatitis C virus; p27; p8; Hepatitis C Virus NS4; HCV NS4 Genotype 5; Hepatitis C Virus NS4 Genotype 5
Citations
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