Human NDUFS8 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-NDUFS8 antibody

Target

NDUFS8

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

4728

UniProt ID

O00217

Antigen Description

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]

Function

4 iron, 4 sulfur cluster binding; contributes_to NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase (ubiquinone) activity; contributes_to NADH dehydrogenase activity; electron carrier activity; metal ion binding; oxidoreductase activity;

Synonyms

NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 8 (23kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; CI 23k; complex I 23kDa subunit; NADH dehydrogenase [ubiquinone] iron sulfur protein 8; mitochondrial; TYKY; complex I-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; CI-23k; CI23KD;