Product Overview
Blocking peptide for anti-NALP14 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
Antigen Description
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
Synonyms
NLRP14; NLR family, pyrin domain containing 14; NOD5; PAN8; GC-LRR; NALP14; CLR11.2; NACHT, LRR and PYD domains-containing protein 14; NACHT, LRR and PYD containing protein 14; NACHT, leucine rich repeat and PYD containing 14; nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14;
Citations
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Li, FX; Guo, NJ; et al. Inhibition of P2X4 Suppresses Joint Inflammation and Damage in Collagen-Induced Arthritis. INFLAMMATION 37:146-153(2014).
Perco, P; Kainz, A; et al. Histogenomics: Association of Gene Expression Patterns With Histological Parameters in Kidney Biopsies. TRANSPLANTATION 87:290-295(2009).